This paper puts forward a new idea and related algorithms for Uyghur segmentation. The word based Bi-gram and contextual information are derived from large scale raw corpus automatically, and according to the Uyghur word association rules, the liner combinations of mutual information, difference of t-test and dual adjacent entropy are taken as a new measurement to estimate the association strength between two adjacent Uyghur words. The weakly associated inter-word position is taken as a segmentation point and the perfect word strings both on its semantics and structural integrity, not just the words separated by spaces, is obtained. The experimental result on large-scale corpus shows that the proposed algorithm achieves 88.21% segmentation accuracy.